Quetiapine Fumarate

Product Description

 Quetiapine Fumarate Description

Chemical Name Quetiapine fumarate is the fumarate salt of 224dibenzobf14thiazepin11yl1piperazinylethoxyethanol

Molecular Formula C42H50N6O4S2  C4H4O4

Molecular Weight 88311 gmol fumarate salt

Appearance Quetiapine fumarate appears as a white to offwhite crystalline powder

Assay Contains not less than 980 and not more than 1020 of C42H50N6O4S2  C4H4O4 calculated on the dried basis

Identification Identification of quetiapine fumarate is confirmed using infrared absorption spectrophotometry and chromatographic methods

Solubility Quetiapine fumarate is practically insoluble in water freely soluble in methanol sparingly soluble in ethanol and slightly soluble in dichloromethane

Melting Point The melting point of quetiapine fumarate is between 181C and 183C

Storage Store quetiapine fumarate in a wellclosed container protected from light and moisture

Usage Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia bipolar disorder and major depressive disorder It acts by antagonizing multiple neurotransmitter receptors including serotonin 5HT2A and 5HT2C dopamine D1 and D2 histamine H1 and adrenergic alpha1 and alpha2 receptors

This comprehensive description ensures that quetiapine fumarate meets the stringent quality standards required for pharmaceutical use